Bridging the Gap: A High-Acuity Shadowing and Mentorship Experience for Medical-Surgical Nurses
June 10, 2026openalex
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RoadblockMental HealthOpen
Objective psychiatric biomarkers
Psychiatry remains one of the few medical specialties without reliable objective diagnostic biomarkers. Current diagnosis relies on subjective symptom checklists (PHQ-9, HAM-D), leading to heterogeneous patient groups and imprecise treatment selection. Candidate biomarkers span inflammatory markers (CRP, IL-6), HPA axis dysregulation (cortisol), neuroimaging signatures, EEG patterns, and digital phenotyping from smartphone data. No single biomarker or panel has achieved sufficient sensitivity and specificity for clinical adoption.
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